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The mean elimination half-life (T-?) values for naltrexone and 6-?-naltrexol are 4 hours and 13 hours, respectively. Naltrexone and 6-?-naltrexol are dose proportional in terms of AUC and Cmax over the range of 50 to 200 mg and do not accumulate after 100 mg daily doses.
Low-dose naltrexone (LDN) describes the off-label use of the medication naltrexone at low doses for diseases such as multiple sclerosis. Naltrexone is typically prescribed for opioid dependence or alcohol dependence, as it is a strong opioid antagonist.
You should tell your doctor if any of the following side effects become severe or don't go away: Nausea, vomiting, diarrhea, or constipation. Stomach pain or cramping. Loss of appetite. Headache. Dizziness. Nervousness, irritability, or anxiety. Tearfulness. Increased or decreased energy.
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Taking large amounts of this drug can induce naltrexone overdose symptoms. Do not take narcotic painkillers or drink alcohol while you are using naltrexone, as doing so can cause adverse side effects, including opioid overdose or alcohol poisoning.
What will happen if a patient drinks alcohol while taking naltrexone? Naltrexone does not reduce the effects of alcohol that impair coordination and judgment. Naltrexone may reduce the feeling of intoxication and the desire to drink more, but it will not cause a severe physical response to drinking. 5.
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